Tissue Lysates
Sino Biological Recombinant Human Claudin-4/CLDN4 Protein (VLP, Full-length, Flag Tag)
A DNA sequence encoding the Human CLDN4-VLP (Full Length) (O14493) (Met1-Val209) was fused with a flag tag at the C-terminus.
Sino Biological Recombinant Human GLP1R Protein (Nanodisc, Flag-His Tag)
A DNA sequence encoding the Human GLP1R (P43220) (Arg24-Phe257) & (Glu262-Lys437) was expressed and linked by a Fusion protein, with polyhistidine tag and Flag tag at the N-terminus. Within the expressed regions, there are several proprietary thermostabilizing mutations. This protein was prepared using our Nanodisc platform.Nanodisc is a versatile tool for studying membrane proteins. Using styrene-maleic acid (SMA) copolymer, membrane proteins can be extracted directly from prokaryotic and eukaryotic expression systems in the absence of detergents to preserve the protein structure and function better. Compared to membrane scaffold proteins (MSPs) nanodiscs, SMA nanodiscs also have the advantage of preserving proteins' nature by maintaining native lipids surrounded without introducing any heterologous proteins, which allows studies of protein structure and functions in a native-like environment.
FOCUS BIOMOLECULES Biochemical Reagents, Mito-Photo-DNP, Mitochondria specific, photo-activated protonophore, CAS Unknown, 98% by TLC/NMR (Conforms)
Biochemical Reagents, Mito-Photo-DNP, Mitochondria specific, photo-activated protonophore, CAS Unknown, 98% by TLC/NMR (Conforms), Mitochondria-targeted, photo-activated protonophore.1 This novel tool consists of three structural units, a caged protonophore, a photocleavable linker coupled to a triphenylphosphonium moiety which confers selective uptake by the mitochondria.2 Cells are treated with Mito-Photo-DNP at 200 nM and irradiated with UV light at 355 nm. Mito-Photo-DNP can be employed for selective uncoupling of either individual or a small number of mitochondria within a cell when used with fluorescence imaging.1,3
Cayman Chemical 1ArachIdonyld5racglycero 100ug
An internal standard for the quantification of 1-AG by GC- or LC-MS
Cayman Chemical SynthetIc FustIn 1mg
A flavanone with diverse biological activities; enhances epigallocatechin-3-O-gallate-induced decreases in the viability of U266 cells at 5 and 10 µM; inhibits increases in blood glucose levels, as well as serum total cholesterol, triglyceride, and MDA levels, in a mouse model of streptozotocin-induced diabetes at 50 and 100 mg/kg; prevents Aβ42-induced decreases in contextual- and tone fear conditioning freezing time in mice at 100 mg/kg
Cayman Chemical 17-trns ProstaglndIn E3 100ug
17-trans PGE3 is an isomer of PGE3 which could theoretically result from the COX metabolism of dietary trans-fatty acids.{5470} There are no published reports on the biological activity of this compound.